Emotional or physical stress
A cold, fever, or other illness
Weakened immunity
Hormonal shifts (like during menstruation)
Sun exposure—especially on your lips
Fatigue or sleep deprivation
Cold sores commonly appear around the mouth, nose, chin, or cheeks.
Early Warning Signs
Cold sores often give subtle clues before making their full appearance:
Tingling, itching, or burning near the lips
Redness or slight swelling
Within 1–2 days: small blisters form, burst, and crust over
Healing usually takes 2–4 weeks, depending on care
Starting treatment early can ease symptoms and shorten recovery.
Treatment Options
Though there’s no permanent cure, treatment can help you manage outbreaks:
Type Examples Purpose
Antiviral meds Acyclovir, Valacyclovir Best taken at first signs
OTC creams Docosanol, Lidocaine Reduces pain and swelling
Pain relievers Ibuprofen, Acetaminophen Eases discomfort
Natural Soothers
Some gentle remedies may calm irritation:
