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A well-known over-the-counter drug found in homes across America may be more dangerous than people realize. Tylenol PM, a common nighttime pain reliever, can lead to organ failure if taken too often or in high doses.

The warning comes from Dr. Ethan Melillo, a pharmacist from Rhode Island, who recently shared his concerns online. He warns that many people assume Tylenol PM is harmless because it’s sold over the counter.

Let’s explore what makes this acetaminophen-based sleep aid potentially harmful, and what safer alternatives are available.

What’s in Tylenol PM?
Tylenol PM contains two active ingredients:

Acetaminophen, which relieves pain and reduces fever

Diphenhydramine, an antihistamine known for its sedative effects
This over-the-counter sleep and pain reliever helps users fall asleep while also relieving mild aches and pains. Many people use it for discomfort that keeps them awake at night. While it may seem like a simple solution, frequent use can pose serious risks to liver and kidney health.

Hidden Risks to Liver and Kidney Health

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