Crusty sore on my lip won’t go away… How to get red at home

A sore on your lip that won’t heal can be uncomfortable and worrying. While I can’t diagnose you, I can share some helpful information about what might be going on and what you can do in the meantime until you’re able to see a doctor.

Common causes of a crusty lip sore

  • Cold sores (Herpes simplex virus): Often start as tingling or burning, then form blisters that crust over. They can recur.
  • Canker sores: Usually inside the mouth but sometimes near the lips. Painful but not contagious.
  • Angular cheilitis: Cracks and sores at the corners of the mouth, often caused by yeast, bacteria, or irritation.
  • Injury/irritation: Biting your lip, sunburn, or even harsh toothpaste/lip balm can cause a sore that doesn’t heal quickly.
  • More serious issues: A sore that lingers beyond 2–3 weeks without healing could sometimes be linked to skin conditions, infections, or rarely, oral cancer — which is why a medical evaluation is important if it continues.

What you can do at home

  • Keep it clean and dry: Gently wash with mild soap and water.
  • Moisturize: Use plain petroleum jelly to prevent cracking.
  • Avoid irritants: Spicy, acidic foods and alcohol-based mouthwash can make it worse.
  • Cold compress: Helps reduce pain and inflammation.
  • Over-the-counter creams: If it seems like a cold sore, antiviral creams (like docosanol/Abreva) may shorten healing.

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